Log file for Protein Box Bot
Log page index: User:ProteinBoxBot/PBB_Log_Index
Protein Status Quick Log - Date: 19:24, 4 November 2007 (UTC)
Proteins without matches (16)
Proteins with a High Potential Match (8)
Redirected Proteins (1)
Created (3)
Manual Inspection (Page not found) (21)
Updated (1)
Protein Status Grid - Date: 19:24, 4 November 2007 (UTC)
Vebose Log - Date: 19:24, 4 November 2007 (UTC)
CCNA2
- INFO : Beginning work on CCNA2...
- UPLOAD : Added new Image to wiki:
- AMBIGUITY : Did not locate an acceptable page to update.
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->{{PBB_Controls| update_page = yes | require_manual_inspection = no | update_protein_box = yes| update_summary = yes| update_citations = yes}}<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->{{GNF_Protein_box | image = PBB_Protein_CCNA2_image.jpg | image_source = ] rendering based on 1e9h. | PDB = {{PDB2|1e9h}}, {{PDB2|1fin}}, {{PDB2|1fvv}}, {{PDB2|1gy3}}, {{PDB2|1h1p}}, {{PDB2|1h1q}}, {{PDB2|1h1r}}, {{PDB2|1h1s}}, {{PDB2|1h24}}, {{PDB2|1h25}}, {{PDB2|1h26}}, {{PDB2|1h27}}, {{PDB2|1h28}}, {{PDB2|1jst}}, {{PDB2|1jsu}}, {{PDB2|1ogu}}, {{PDB2|1oi9}}, {{PDB2|1oiu}}, {{PDB2|1oiy}}, {{PDB2|1okv}}, {{PDB2|1okw}}, {{PDB2|1ol1}}, {{PDB2|1ol2}}, {{PDB2|1p5e}}, {{PDB2|1pkd}}, {{PDB2|1qmz}}, {{PDB2|1urc}}, {{PDB2|1vin}}, {{PDB2|1vyw}}, {{PDB2|2bkz}}, {{PDB2|2bpm}}, {{PDB2|2c4g}}, {{PDB2|2c5n}}, {{PDB2|2c5o}}, {{PDB2|2c5p}}, {{PDB2|2c5v}}, {{PDB2|2c5x}}, {{PDB2|2c6t}}, {{PDB2|2cch}}, {{PDB2|2cci}}, {{PDB2|2cjm}}, {{PDB2|2g9x}}, {{PDB2|2i40}}, {{PDB2|2iw6}}, {{PDB2|2iw8}}, {{PDB2|2iw9}}, {{PDB2|2uue}} | Name = Cyclin A2 | HGNCid = 1578 | Symbol = CCNA2 | AltSymbols =; CCN1; CCNA | OMIM = 123835 | ECnumber = | Homologene = 55562 | MGIid = 108069 | GeneAtlas_image1 = PBB_GE_CCNA2_203418_at_tn.png | GeneAtlas_image2 = PBB_GE_CCNA2_213226_at_tn.png | Function = | Component = {{GNF_GO|id=GO:0001939 |text = female pronucleus}} {{GNF_GO|id=GO:0001940 |text = male pronucleus}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} | Process = {{GNF_GO|id=GO:0000079 |text = regulation of cyclin-dependent protein kinase activity}} {{GNF_GO|id=GO:0007049 |text = cell cycle}} {{GNF_GO|id=GO:0007067 |text = mitosis}} {{GNF_GO|id=GO:0007095 |text = mitotic cell cycle G2/M transition DNA damage checkpoint}} {{GNF_GO|id=GO:0045941 |text = positive regulation of transcription}} {{GNF_GO|id=GO:0051301 |text = cell division}} | Orthologs = {{GNF_Ortholog_box | Hs_EntrezGene = 890 | Hs_Ensembl = ENSG00000145386 | Hs_RefseqProtein = NP_001228 | Hs_RefseqmRNA = NM_001237 | Hs_GenLoc_db = | Hs_GenLoc_chr = 4 | Hs_GenLoc_start = 122958002 | Hs_GenLoc_end = 122964505 | Hs_Uniprot = P20248 | Mm_EntrezGene = 12428 | Mm_Ensembl = ENSMUSG00000027715 | Mm_RefseqmRNA = NM_009828 | Mm_RefseqProtein = NP_033958 | Mm_GenLoc_db = | Mm_GenLoc_chr = 3 | Mm_GenLoc_start = 36756415 | Mm_GenLoc_end = 36763547 | Mm_Uniprot = Q8BRG1 }}}}'''Cyclin A2''', also known as '''CCNA2''', is a human ].<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->{{PBB_Summary| section_title = | summary_text = The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.<ref>{{cite web | title = Entrez Gene: CCNA2 cyclin A2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=890| accessdate = }}</ref>}}==References=={{reflist}}{{refbegin | 2}}{{PBB_Further_reading | citations = }}{{refend}}{{protein-stub}}CCR2
- INFO : Beginning work on CCR2...
- AMBIGUITY : Did not locate an acceptable page to update.
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->{{PBB_Controls| update_page = yes | require_manual_inspection = no | update_protein_box = yes| update_summary = yes| update_citations = yes}}<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->{{GNF_Protein_box | image = | image_source = | PDB = | Name = Chemokine (C-C motif) receptor 2 | HGNCid = 1603 | Symbol = CCR2 | AltSymbols =; CC-CKR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R | OMIM = 601267 | ECnumber = | Homologene = 537 | MGIid = 106185 | Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0016493 |text = C-C chemokine receptor activity}} {{GNF_GO|id=GO:0031727 |text = CCR2 chemokine receptor binding}} | Component = {{GNF_GO|id=GO:0005625 |text = soluble fraction}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} | Process = {{GNF_GO|id=GO:0006935 |text = chemotaxis}} {{GNF_GO|id=GO:0006954 |text = inflammatory response}} {{GNF_GO|id=GO:0006955 |text = immune response}} {{GNF_GO|id=GO:0006968 |text = cellular defense response}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007194 |text = negative regulation of adenylate cyclase activity}} {{GNF_GO|id=GO:0007204 |text = elevation of cytosolic calcium ion concentration}} {{GNF_GO|id=GO:0007259 |text = JAK-STAT cascade}} {{GNF_GO|id=GO:0019221 |text = cytokine and chemokine mediated signaling pathway}} {{GNF_GO|id=GO:0019735 |text = antimicrobial humoral response}} | Orthologs = {{GNF_Ortholog_box | Hs_EntrezGene = 1231 | Hs_Ensembl = | Hs_RefseqProtein = NP_000638 | Hs_RefseqmRNA = NM_000647 | Hs_GenLoc_db = | Hs_GenLoc_chr = | Hs_GenLoc_start = | Hs_GenLoc_end = | Hs_Uniprot = | Mm_EntrezGene = 12772 | Mm_Ensembl = ENSMUSG00000049103 | Mm_RefseqmRNA = NM_009915 | Mm_RefseqProtein = NP_034045 | Mm_GenLoc_db = | Mm_GenLoc_chr = 9 | Mm_GenLoc_start = 123954462 | Mm_GenLoc_end = 123957349 | Mm_Uniprot = Q3TRK1 }}}}'''Chemokine (C-C motif) receptor 2''', also known as '''CCR2''', is a human ].<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->{{PBB_Summary| section_title = | summary_text = This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.<ref>{{cite web | title = Entrez Gene: CCR2 chemokine (C-C motif) receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1231| accessdate = }}</ref>}}==References=={{reflist}}==Further reading=={{refbegin | 2}}{{PBB_Further_reading | citations = *{{cite journal | author=Sozzani S, Introna M, Bernasconi S, ''et al.'' |title=MCP-1 and CCR2 in HIV infection: regulation of agonist and receptor expression. |journal=J. Leukoc. Biol. |volume=62 |issue= 1 |pages= 30-3 |year= 1997 |pmid= 9225989 |doi= }}*{{cite journal | author=Cunningham AL, Li S, Juarez J, ''et al.'' |title=The level of HIV infection of macrophages is determined by interaction of viral and host cell genotypes. |journal=J. Leukoc. Biol. |volume=68 |issue= 3 |pages= 311-7 |year= 2000 |pmid= 10985245 |doi= }}}}{{refend}}{{protein-stub}}CD46
- INFO : Beginning work on CD46...
- UPLOAD : Added new Image to wiki:
- AMBIGUITY : Did not locate an acceptable page to update.
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->{{PBB_Controls| update_page = y
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